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Image Search Results
Journal: Molecular Medicine Reports
Article Title: Mitogen-activated protein kinase mediates mevalonate-stimulated human mesangial cell proliferation
doi: 10.3892/mmr.2015.3715
Figure Lengend Snippet: (A) MVA had no significant effect on the expression of p-p38 MAPK. SB203580 markedly inhibited the expression of p-p38 MAPK. (B) MVA significantly upregulated the expression of p-JNK (P<0.05, vs. control). SP600125 markedly inhibited the expression of p-JNK. (C) MVA significantly upregulated p-ERK expression (P<0.05, vs. control). PD98059 markedly inhibited the expression of p-ERK. The results are presented as the mean ± standard deviation * P<0.05, vs. MVA only. MVA, mevalonate; Cont, control; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; JNK, c-Jun NH2-teminal kinase.
Article Snippet: The HMCs (1×10 5 cells/ml) were then cultured with MVA (1×10 −7 mol/l), either alone or in the presence of 50 μ mol/l PD98059, an
Techniques: Expressing, Control, Standard Deviation